by The Welthi Bureau | 22 DEC 2017
The Indian Journal of Cardiovascular disease in women has published five papers on cardiovascular diseases in women and why women suffer from heart problems. Dr. Sumeet Sinha, senior consultant interventional cardiologist and Head Department Of Cardiology at Virinchi Hospitals elaborates
What are the reasons found in these papers for the women to suffer from heart problems?
Ans. Cardiovascular diseases in women are caused due to low hdl(good cholesterol), high BMI body mass index). Besides this, high BP, diabetes, sedentary life style, stressful work conditions, compromised diet.
How many Indian women have been covered?
Ans. This study covered 1.6 lakh urban Indians out of which 32% were women, and of these 92% were less than 60 years of age.
Are the features different from those in the West?
Ans. Diabetes, hypertension, and other metabolic factors play a very important role in the onset of cardio vascular diseases in young women. Complex lesions showed greater predominance in females than in males. Truncal obesity and increased body mass index (bmi) have recently been proposed as potential independent risk factors, particularly in young women.
Sagittal abdominal diameter to skin fold ratio seems to be a good indicator in predicting premature heart problems even better than bmi and waist circumference of 31.
Does this help in better treatment? Are the drugs given to women different from those give to men?
Ans. Women even at a younger age are susceptible to heart problems especially with gestational diabetes and anaemia also plays a role. Obesity and sedentary life style needs to be tackled aggressively. Hence treatment & correction of all risk factors, regular screening for heart diseases play an important role in preventing and treating heart diseases in women.
Treatment is essentially the same as men, though some antihypertensive drugs work better in women.
What is the role of sex chromosomes in heart problems? How does it affect the body? How does it affect the treatment regime?
Ans 5. Cardiovascular disease in women differs in clinical presentation, path physiology and prognosis from that in men. The role of estrogens and androgens may help explain such sex dimorphisms, being involved in cardiac function, endothelial function and vascular tone. Men develop hypertension at younger ages than women, thus carrying an increased life-long burden of disease including the risk of stroke.
Genetic risk for development of other cardiovascular disease apart from hypertension may be imparted simply by inheriting the Y chromosome. Since in males, the Y chromosome also includes genes involved with activation affecting innate immunity.
In particular, the cardio protective effect of estrogen replacement therapy is observed in postmenopausal women in a time-dependent manner, i.e. when it is initiated at their first menopausal symptoms.
Postmenopausal women, beyond aged men, may also benefit from testosterone supplementation therapy. Testosterone has been found to be an effective and safe therapy for elderly women with chronic heart failure.
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